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Postdoctoral Fellow in Medicine - Clinical Pharmacology

Indiana University

Job Description

Title Postdoctoral Fellow in Medicine - Clinical Pharmacology
Specific Title
Appointment Type Postdoctoral Fellow
Department IUSM - Medicine - Clinical Pharmacology
Campus IU School of Medicine Indianapolis
Position Summary
The Disease and Therapeutic Response Modeling and Simulation Program within the Division of Clinical Pharmacology in the Department of Medicine at Indiana University School of Medicine seeks applications for a postdoctoral fellowship in pharmacometrics. Projects span across the translational research paradigm, from preclinical drug discovery to precision therapeutics, in a variety of therapeutic areas, including oncology, Alzheimer’s disease, obstetrics, and pediatrics.
Our training program is highly individualized. Universally, training entails the application of non-linear mixed effects modeling, physiologically based pharmacokinetics, quantitative systems pharmacology, Bayesian modeling, and Monte-Carlo Simulation techniques in a setting of applied or methodological/theoretical research. The group offers a stimulating modeling environment by encouraging active interactions and collaborations with scientists trained in biostatistics, computational biology, and bioinformatics. Trainees work closely with clinical pharmacology fellows and are expected to participate in the Division’s didactics, seminars, and journal clubs.
Projects focus on the development of pharmacometric models used to describe and predict pharmacokinetics and pharmacodynamics as well as patho-physiological processes relating to disease state and/or disease progression. Applied research projects are not limited to only model development and hypothesis testing, but also include the potential use of models to guide experimental/clinical trial design and for hypothesis generation (e.g. mechanistic models and/or systems pharmacology).
About the School and Department: The Indiana University School of Medicine https://medicine.iu.edu/ is the largest medical school in the US and is annually ranked among the top medical schools in the US by US News & World Report. Please visit http://medicine.iupui.edu for additional information about the Department of Medicine.
About the Campus: To learn more about the Indiana University-Purdue University Indianapolis campus, please visit: http://www.iupui.edu/about/
About the City: Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues, and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https://faculty.medicine.iu.edu/relocation/.
As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity, and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
Basic Qualifications
Our interdisciplinary team is looking for a motivated, ambitious, and creative individual with excellent written and verbal communication skills.
Doctorate or terminal degree required. PharmD, MD, or PhD in pharmacology, systems biology/pharmacology, pharmacometrics, biostatistics, computational biology, or related fields.
Experience with R, NONMEM, Monolix, and/or PBPK modeling is prerequisite. Applicants must have demonstrated experience and proficiency in some aspect of mathematical modeling as well as a basic knowledge of statistics, biology, physiology and pharmacology. Excellent spoken and written English communication skills are prerequisite.
Department Contact for Questions
Cheryl Weatherholt
Additional Qualifications
Special Instructions
Priority Application Review Deadline
Expected Start Date
OAA # IUSM-01485-2022

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