|Job Title||Post-Doctoral Scholar|
|Department Name||7H030:SANDERS-BROWN CTR ON AGING|
|Work Location||Lexington, KY|
|Type of Position||Temporary|
|Position Time Status||Full-Time|
|Required Education|| |
must hold PhD
|Required Related Experience|| |
|Required License/Registration/Certification|| |
|Physical Requirements|| |
May require long periods or sitting and/or standing; may require lifting up to 25lbs
Primarily days but may require occasional work on evenings or weekends
|Job Summary|| |
The Maj-Linda Selenica’s laboratory in the Sanders-Brown Center of Aging, Departments of Biochemistry at University of Kentucky is currently looking for highly skilled and motivated molecular and cell biologists to be the drivers of our efforts to unravel mechanisms contributing to the TDP-43 pathology of limbic-predominant age-related TDP-43 encephalopathy (LATE) and other Alzheimer’s Disease Related Dementias (ADRD). Core areas of focus will be understanding the role of citrullination and other PTMs in the TDP-43 protein structure, biology, and pathology into both in vitro (induced pluripotent stem cell models) and in vivo systems (mouse models) to understand the clinical outcomes of TDP-43 pathogenesis in LATE and ADRD. In particular, our lab concentrates on identifying the role of citrullination in recombinant TDP-43 liquid-liquid phase separation and aggregation kinetics (ThT, TEM, FRAP) and dissecting the molecular, cellular, and tissue-level mechanisms by which this PTM and the associated enzymes (e.g., PADs) modulate disease risk, with a major focus on cell-specific role on the regional milieu and disease pathology. The candidate will join a multidisciplinary and highly collaborative research team that includes geneticists, immunologists, biostatisticians, neuroscientists, and neuropathologist at the Sanders-Brown Center on Aging as one of the leading centers in the country for ADRD and LATE research and clinical interventions.
The Sanders-Brown Center on Aging and Selenica Laboratory strongly believes that diversity and inclusion is a driver for excellence. We share a common devotion to delivering exceptional patient care. Yet we’re as diverse as the city we call home- culturally, ethically, in outlook and lifestyle. When you join us, you become a part of Sanders- Brown Center on Aging unrivaled record of achievement, education, and advancement as we revolutionize healthcare delivery together.
We work hard to recruit and retain the best people, and to create a welcoming, nurturing work environment where you have the opportunity and support to develop professionally. We share the belief that all employees, regardless of job title or expertise, have an impact on quality patient care.
Explore more about this opportunity and how you can help us write a new chapter in our story!
|Skills / Knowledge / Abilities|| |
|Does this position have supervisory responsibilities?||No|
|Preferred Education/Experience|| |
|Deadline to Apply||09/21/2023|
|University Community of Inclusion|| |
The University of Kentucky is committed to a diverse and inclusive workforce by ensuring all our students, faculty, and staff work in an environment of openness and acceptance. We strive to foster a community where people of all backgrounds, identities, and perspectives can feel secure and welcome. We also value the well-being of each of our employees and are dedicated to creating a healthy place to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors the University of Kentucky is a Tobacco & Drug Free campus.
*Please mention you saw this ad on PhdJobs.*