At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie

About the Role:

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• Design and execute laboratory experiments to optimize and characterize conjugation chemistries and downstream purification processes for peptide-based bioconjugates

• Development and optimization of conjugation protocols utilizing novel chemistries and technologies

• Preferably, experienced with conjugation to different modalities (Antibody, Protein, Peptide, Small molecules)

• Process development on both upstream and downstream process, lead projects and teams towards agreed upon goals, ultimately working towards GMP manufacturing of development candidate

• Aid in lab setup, instrument purchase, installation, and ongoing lab operations

• Effective communication of scientific rationale, results and interpretation at project, team, and departmental meetings, contributing to strategic discussions

• Active management of CDMO for non-GMP/GMP drug substance manufacturing

• May provide input for portion(s) of CMC regulatory documentation and supporting work

• Collaborate with cross-functional teams to ensure successful technology transfer from the laboratory to manufacturing

• Other duties as assigned

• BS/BA degree in Chemistry, chemical engineering, or other similar scientific field and 5+ years of experience in experience in pharmaceutical/process development field, including API manufacturing experience OR

• MS/MA degree in Chemistry, chemical engineering, or other similar scientific field and 3+ years of similar experience above OR

• PhD in Chemistry, chemical engineering, or other similar scientific field and some relevant industry experience; may include postdoc experience

• Demonstrates solid level of understanding project / group goals and methods

• Consistently recognizes anomalous and inconsistent results and interprets experimental outcomes

• Able to explain the process behind the data and implications of the results

• Strong knowledge of one or more scientific disciplines, becoming expert in one discipline

• Strong knowledge of scientific principles, methods and techniques.

• Strong knowledge and demonstrated ability working with a variety of laboratory equipment/tools

• Ability to work as part of a team; may train lower levels

• Excellent computer skills

• Strong communications, problem-solving, analytical thinking skills

• Detail oriented yet can see broader picture of scientific impact on team

• Ability to meet multiple deadlines, with a high degree of accuracy and efficiency

• Strong project management skills

• Ability to build and manage internal and external working relationships

• Experienced in bioconjugation chemistry and downstream purification processes, with hands-on experience in the generation and characterization of bioconjugates

• Excellent communication and collaboration skills, with ability to collaborate effectively within cross-functional teams

• Excellent analytical, communication, organizational, and presentation skills are essential

• Demonstration of cross-functional understanding related to drug development

• Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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